Comparison of Two Different Forms of Nitroglycerin In Anesthesia of The Patients Under Phacoemulsification Surgery

Comparison Between The Hemodynamic Effects of Cutaneous Nitroglycerin And Intravenous Nitrogltcerin In Patients Under Phacoemulsification surgery surgery

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201105125751N2

Enrollment

Registered

2012-07-20

Start date

2012-07-24

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Senile cataract, unspecified

Interventions

Intervention 1: In Interventional Group: Skin Patch of Nitroglycerin up to 2 cm Anterior Chest Wall 40 minutes Before Induction of Anesthesia. Intervention 2: In Control Group: Intravenous Nitroglyce

Treatment - Drugs

In Interventional Group: Skin Patch of Nitroglycerin up to 2 cm Anterior Chest Wall 40 minutes Before Induction of Anesthesia

In Control Group: Intravenous Nitroglycerin 0.5 microgram/kg/minute Before Induction of anesthesia

Eligibility

Sex/Gender

All

Age

50 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion Criteria consist of: Known Ischemic Heart Disease Patients Candidate for Phacoemulsification Surgery Exclusion criteria Consist of : Uncontrolled Type 1 and 2 Diabetics; Patients With Severe Left ventricular Dysfunction

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Systolic Blood Pressure. Timepoint: Before Induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.;Diastolic Blood Pressure. Timepoint: Before induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.;Heart Rate. Timepoint: Before induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.;Mean Arterial Pressure. Timepoint: Before induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.	—

Measure

Time frame

Systolic Blood Pressure. Timepoint: Before Induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.;Diastolic Blood Pressure. Timepoint: Before induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.;Heart Rate. Timepoint: Before induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.;Mean Arterial Pressure. Timepoint: Before induction of anesthesia; 1 minute after induction; 3 minutes after induction; after LMA insersion; after surgical stimulation; post extubation; 2 hours postoperation. Method of measurement: Noninvasive Blood Pressure Monitoring.

—

Secondary

Measure	Time frame
New Changes In Electrocardiography. Timepoint: Perioperative Period; 2 hours after operation. Method of measurement: Noninvasive Blood Pressure Monitoring.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAbdolrasoul Anvaripour

Bushehr University of Medical Sciences

a.anvari.p@hotmail.com anvari@bpums.ac.ir+7 712526802

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026