Colon cancer. Malignant neoplasm of colon, unspecified
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group will receive 2 royal jelly tablets daily, for 4 weeks while waiting for surgery. Manufacturer: Kooze Asal Company. Intervention 2
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age 18 to 65 years Diagnosed with colon cancer and needing surgery The cancer is in the second or third stage.
Exclusion criteria
Exclusion criteria: Pregnancy The immunodeficiency Progressive infection Disorder in the respiratory system (arterial oxygen pressure less than 70 mm Hg) Cardiovascular disorder Renal system disorder Hepatic disorders The level of hepatic enzymes is more than three times the upper limit of normal Serum hemoglobin level less than 8 g/dL with a sudden drop (more than 2 g/dL) in the last month. Total serum bilirubin greater than 2 mg/dL Serum creatinine greater than 2 mg/dL Creatinine clearance less than 60 ml/min
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Fatigue. Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: The Fatigue will assess with analogue fatigue scale (VAFS) and fatigue severity scale (FSS). | — |
Secondary
| Measure | Time frame |
|---|---|
| Weight. Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: The weight is calculated by the scale.;Quality of life. Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: The quality of life will assess with questionnaire of cancer patients-Aronson (1987) and Fatigue with analogue fatigue scale (VAFS) and fatigue severity scale (FSS).;Body Mass Index (BMI ). Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: Body Mass Index ( BMI ) will calculate with BMI formula.;C-reactive protein. Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: 5 cc of blood is taken to measure the inflammatory factors and they are measured by ELISA kits.;Tumor necrosis factor-a. Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: 5 cc of blood is taken to measure the inflammatory factors and they are measured by ELISA kits.;Interleukin-6. Timepoint: At the beginning of the research, after 4 weeks of intervention and before surgery. Method of measurement: 5 cc of blood is taken to measure the inflammatory factors and they are measured by ELISA kits. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Shadnoush
National Nutrition and Food Technology Research Institute
Outcome results
None listed