The amount of pain after open heart surgery.
Conditions
Interventions
Intervention 1: Intervention group: Familact supplement of bio-fermentation company contains probiotic mixture including 7 stable and frozen strains: Lactobacillus acidophilus CFU (109 × 2), Lactobaci
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Willingness to participate in the study and completion of informed written consent People who, at the discretion of a cardiologist, need open heart surgery Age over 40 years Lack of gastrointestinal sensitivity to probiotics Body mass index greater than 18 Do not drink alcohol or use drugs and anti-inflammatory drugs Do not take multivitamin and mineral supplements, do not take clozapine, theophylline, caffeine, phenacetine and tacrine Do not take interfering drugs on the surface of the intestinal microbiome
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of pain. Timepoint: Immediately after regaining consciousness, 12 hours and 24 hours later regaining consciousness. Method of measurement: Visual Analog Scale.;Measurement of gut microbiome. Timepoint: Start and end of the study. Method of measurement: gut microbiome genome sequencing technique. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMahdi Shadnoush
Shahid Beheshti University of Medical Sciences
Outcome results
None listed