Effect of magnesium on acute myocardial infarction

Effect of intravenous magnesium sulfate on blood complement,quantitative CRP level and leukocytes count in patient with acute myocardial infarction who treated with streptokinase

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201105096309N1

Enrollment

Registered

2011-05-23

Start date

2010-10-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction. Myocardial infarction specified as acute or with a stated duration of 4 weeks (28 dayes)or less from onset

Interventions

1gr intravenus magnesium sulfate during 1 minute as a loading dose before streptokinase injection and 8gr magnesium sulfate infusion during 24 hours,we don"t use of placebo.

Treatment - Drugs

1gr intravenus magnesium sulfate during 1 minute as a loading dose before streptokinase injection and 8gr magnesium sulfate infusion during 24 hours,we don"t use of placebo

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients with acute myocardial infarction who treated with streptokinase be enrolled in the study Exclusion criteria are:cardiogenic shock,systolic blood pressure<90,AV block grade2&3,illiac resection,renal failure,collagen vascular diseases,alcohol&drug abuse,chemotherapy and consumption of immunosuppresive drugs during a past year

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
CH50. Timepoint: 6,24&48 after injection of streptokinase. Method of measurement: Neflometry.;C3. Timepoint: 6,24&48 hours ater injection of streptokinase. Method of measurement: Radial Immunodiffusion.;C4. Timepoint: 6,24&48hours ater injection of streptokinase. Method of measurement: Radial Immunodiffusion.;CRP. Timepoint: 6,24,48 houres after injection of streptokinase. Method of measurement: Elisa.;Leukocytes count. Timepoint: 6,24,48 houres after injection of streptokinase. Method of measurement: CBC H1 method.	—

Measure

Time frame

CH50. Timepoint: 6,24&48 after injection of streptokinase. Method of measurement: Neflometry.;C3. Timepoint: 6,24&48 hours ater injection of streptokinase. Method of measurement: Radial Immunodiffusion.;C4. Timepoint: 6,24&48hours ater injection of streptokinase. Method of measurement: Radial Immunodiffusion.;CRP. Timepoint: 6,24,48 houres after injection of streptokinase. Method of measurement: Elisa.;Leukocytes count. Timepoint: 6,24,48 houres after injection of streptokinase. Method of measurement: CBC H1 method.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Hashem Kazerani

Kermanshah University Of Medical Science

Dr-hashemkazerani@kums.ac.ir+98 83 1836 0041

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026