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Evalution of intracuff dexamethasone on postextubation reactions

Evaluation of intracuff dexamethasone on Sore throat and hoarseness and laryngospasm frequency a

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201105095536N3
Enrollment
180
Registered
2011-11-22
Start date
2009-08-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complication of intubation. Failed or difficult intubation

Interventions

Intervention 1: The observer will fill endotracheal cuff randomly with normal saline in group N. Intervention 2: The observer will fill endotracheal cuff randomly with Lidocaine in group L. Interventi
Behavior
Prevention
The observer will fill endotracheal cuff randomly with normal saline in group N.
The observer will fill endotracheal cuff randomly with Lidocaine in group L.
The observer will fill endotracheal cuff randomly with Dexamethasone in group D.

Sponsors

Research Assistance of AJA University of Medical Science
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: The inclusion criteria for this study are being: male sex, non-smoker, not suffering from any disease related to air ways like asthma, bronchitis and amphysma, not having cold during last 6 weaks, not using corticosteroids and analgesics before operation. Our exclusion criteria are factors predictive of difficult intubation (number of tracheal intubation attempts), and the need for a nasogastric tube Patients with any preoperative sore throat or hoarseness or any airway condition resulting in an ASA physical status greater than II3,12.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Cough. Timepoint: Every 6 hours. Method of measurement: History taking and physical examination.;Sore throat. Timepoint: Every 6 hours. Method of measurement: History taking and physical examination.;Laryngospasm. Timepoint: Every 6 hours. Method of measurement: Physical examination.

Secondary

MeasureTime frame
Weight. Timepoint: Before start of intervention. Method of measurement: weigh.;Age. Timepoint: Before start of intervention. Method of measurement: Patient identification card.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mohamad Reaz Rafiei

AJA University of Medical Science

mo_rafiei@armyums.ac.ir; rafiei_mohamadreza@yahoo.com; mrafiei2002@yahoo.com+98 31 1263 1587

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026