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Comparison of the effect of tow embryo transfer in the stage of blastocyst and sequential transfer of a cleavage-a blastocyst embryo on pregnancy outcomes Patients who are candidates for frozen embryo transfer and recurrent implantation failure; a randomized clinical trial

Comparison of the effect of tow embryo transfer in the stage of blastocyst and sequential transfer of a cleavage-a blastocyst embryo on pregnancy outcomes Patients who are candidates for frozen embryo transfer and recurrent implantation failure; a randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110509006420N27
Enrollment
140
Registered
2024-01-27
Start date
2024-01-30
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: Infertile people who are candidates for frozen embryo transfer with a history of two implantation failures, if their number of embryos is at least 4, after obtainin

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
No minimum to 45 Years

Inclusion criteria

Inclusion criteria: Candidates for frozen embryo transfer Failure of more than 2 implants The number of frozen embryos is at least four Women under the age of 45

Exclusion criteria

Exclusion criteria: Uncontrolled endocrine diseases (diabetes, hyperthyroid and hypothyroid) Egg donation Uncontrolled autoimmune diseases (lupus and rheumatoid arthritis) Severe uterine adenomyosis Sever Asherman Untreated hydrosalpinx

Design outcomes

Primary

MeasureTime frame
Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Sonography.

Secondary

MeasureTime frame
Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Through the measurement of BHCG.;Twin pregnancy. Timepoint: In the 6th week of pregnancy. Method of measurement: Observation of two gestational sacs in vaginal ultrasound.;The rate of premature abortion. Timepoint: Ten weeks after embryo transfer. Method of measurement: Absence of fetal heartbeat in sonography.;Ectopic pregnancy. Timepoint: After proving chemical pregnancy. Method of measurement: Not increasing beta hCG titer and not seeing pregnancy sac in vaginal ultrasound.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Eftekhar

Yazd University of Medical Sciences

eftekhar@ssu.ac.ir+98 35 3824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026