Sequential transfer of a day 2/3 embryo and day 5/6 embryo compared to one step two day 2/3 embryo transfer

Effect of sequential cleavage and blastocyst embryo transfer compared to one step cleavage embryo transfer on Assisted Reproductive Technology(ART) outcome of patients with at least two and maximum of five embryos, A randomized clinical trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110509006420N26

Enrollment

140

Registered

2023-08-27

Start date

2023-08-27

Completion date

Unknown

Last updated

2024-05-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility

Interventions

Intervention 1: Intervention group: Infertile women candidate for IVF/ICSI, if they are eligible for fresh embryo transfer, and the number of their embryos is at minimum of two and maximum of five, af

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Infertile women candidate for oocyte puncture and fresh embryo transfer with minimum of two and maximum of five embryos

Exclusion criteria

Exclusion criteria: Women with structural and anatomical uterine abnormalities

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Observation of fetal heart activity by transvaginal ultrasonography.	—

Secondary

Measure	Time frame
Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Through blood sample Beta Hcg.;Early misscariage rate. Timepoint: Ten weeks after embryo transfer. Method of measurement: Absence of fetal heart activity in ultrasound.;Ectopic pregnancy. Timepoint: After positive result for chemical pregnancy. Method of measurement: No rise in serum Beta Hcg level and not visualizing intra uterine gestetianal sac in Trans Vaginal Ultrasound.	—

Measure

Time frame

Chemical pregnancy. Timepoint: Two weeks after embryo transfer. Method of measurement: Through blood sample Beta Hcg.;Early misscariage rate. Timepoint: Ten weeks after embryo transfer. Method of measurement: Absence of fetal heart activity in ultrasound.;Ectopic pregnancy. Timepoint: After positive result for chemical pregnancy. Method of measurement: No rise in serum Beta Hcg level and not visualizing intra uterine gestetianal sac in Trans Vaginal Ultrasound.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Eftekhar

Yazd University of Medical Sciences

eftekharmaryam@yahoo.com+98 35 1824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026