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frozen cycles following endometrial preparation with estrogen and progesterone compared with tamoxifen

Evaluation of pregnancy outcomes in frozen cycles following endometrial preparation with estrogen and progesterone compared with tamoxifen in women with Polycystic Ovary Syndrome

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110509006420N23
Enrollment
200
Registered
2021-11-18
Start date
2021-12-06
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female inf

Interventions

Intervention 1: Intervention group: given 20 mg of tamoxifen orally daily from day 3 to 7 of the cycle, and ultrasound is performed on day 10. If there are 14 or more dominant follicles, the ultrasoun

Sponsors

Yazd University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Frozen embryo transfer candidate With polycystic ovary syndrome based on the Rotterdam criteria

Exclusion criteria

Exclusion criteria: Severe male infertility includes cases of azoospermia and sperm from TESE or PESA History of History of uterine surgery such as hysteroscopic surgery Body mass index more than 30 Use of coumarin anticoagulants DVT history pulmonary edema

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy. Timepoint: 15 days after embryo transfer. Method of measurement: Blood laboratory kit.;Clinical pregnancy. Timepoint: 3 weeks after positive beta-h Cg. Method of measurement: Observation of fetal heart activity by transvaginal ultrasonography.

Secondary

MeasureTime frame
Miscarriage rate. Timepoint: Loss of pregnancy before 20 gestational week. Method of measurement: Absence of fetal heart activity in ultra sound sonography.;Implantation rate. Timepoint: 3 weeks after positive beta-h Cg. Method of measurement: Calculated by the number of gestational sacs observed on ultrasound on the number of embryos transferred.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMaryam Eftekhar

Yazd University of Medical Sciences

eftekhar@ssu.ac.ir+98 35 1824 7085

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026