nausea and vomiting. Vomiting following gastrointestinal surgery
Conditions
Interventions
Intervention 1: Ondansetron, 4mg, intravenously, immediately before receiving general anesthesia. Intervention 2: dexamethasone, 8mg, intravenously, immediately before receiving general anesthesia. In
Treatment - Drugs
Ondansetron, 4mg, intravenously, immediately before receiving general anesthesia
dexamethasone, 8mg, intravenously, immediately before receiving general anesthesia
Combination of Ondansetron, 4mg, as well as Dexamethasone, intravenously, immediately before receiving general anesthesia
Sponsors
Kashan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
20 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age between 20-65 years old, referring for elective laparascopic cholecystectomy Excluding criteria: Having nausea and/ or vomiting, taking any antiemetic medication within 48 hrs before surgery, having taken H2 blockers, having a history of motion sickness, pregnancy, menstruation, renal disease with high BUN and Cr, receiving any investigational drug within 30 days prior to the surgery, requiring open approach during Laparoscopic approach
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nausea and vomiting. Timepoint: 6 hours and 24 hours after intervention. Method of measurement: Questionnaires and observation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of anesthesia. Timepoint: Operation from start to end. Method of measurement: Per minute. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Hamid Reza Vafaei
Kashan University of Medical Sciences
Outcome results
None listed