Vaginal Atrophy. Postmenopausal Atrophic Vaginitis
Conditions
Interventions
Intervention 1: Hyaloronic Acid, Vaginal Suppositories of 5 mg single for 2 months. Intervention 2: Vitamin E, Vaginal Suppositories of 1 mg single for 2 months.
Treatment - Drugs
Hyaloronic Acid, Vaginal Suppositories of 5 mg single for 2 months
Vitamin E, Vaginal Suppositories of 1 mg single for 2 months
Sponsors
Vice chancellor for research, Jondi Shapur Ahvaz University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
45 Years to 65 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Age between 45 to 65, Amenorrhea at less 12 month or have hormone test with FSH level more than 40 unit, Presence of normal pap smears, Presenting symptom of vaginal atrophy, Vaginal pH more than 5, Superficial vaginal cells with 5% or less, Have Sexual activity Exclusion criteria: Vaginal infection, Genital Abnormalities, The use of Sex Hormones within the 8 weeks preceding study, Genital Bleeding of unknown Cause, Use of Phytoestrogens such as Soy, Red clover, Fenugreek, Vitex within the last one Month
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Symptoms of Vaginal Atrophy. Timepoint: Before intervention, Two weeks after the intervention, Four weeks after intervention, Eight weeks after intervention. Method of measurement: Composite Score of Vaginal Symptoms. | — |
Secondary
| Measure | Time frame |
|---|---|
| Vaginal Superficial Cells. Timepoint: after intervention, Two months after intervention. Method of measurement: Vaginal Cells Maturation Index.;Vaginal pH. Timepoint: Before intervention, Two months after intervention. Method of measurement: pH Test. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactSara Ziagham
Ahvaz Jundishapur University of Medical Science
Outcome results
None listed