A comparison study of the therapeutic effect of "honey plus coffee" and inhaled Fluticason/Salmetrol on the chronic bronchiolitis in the chemical injured patients following exposure to sulfur mustard

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104294737N4

Enrollment

Registered

2011-05-09

Start date

2010-01-01

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic bronchiolitis. Other specified chronic obstructive pulmonary disease

Interventions

Intervention 1: First intervention group:Spray of Normal saline + A syrup like solution of 500 gr Honey with 70 gr coffee for every one week. (Duration of intervention is 12 weeks). Intervention 2:

Treatment - Drugs

Treatment - Other

First intervention group:Spray of Normal saline + A syrup like solution of 500 gr Honey with 70 gr coffee for every one week. (Duration of intervention is 12 weeks)

Second intervention group:Spray of Fluticason 500 microgr / Salmetrol 100 microgr / daily + A syrup like solution of liquid Glucose. (Duration of intervention is 12 weeks)

Third intervention group: Spray of Salbutamol inhaler 800 microgr daily+ Spray of Beclomethason 1000 microgr daily + A syrup like solution of liquid Glucose. (Duration of intervention is 12 weeks)

Eligibility

Sex/Gender

All

Age

21 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Chemical injured patients (CIPs) symptomatic with: cough, dyspnea, night awakening. Having significant air trapping in High resolution computed tomography (HRCT) and a marked increase of residual volume in pulmonary function tests (PFT). Exclusion criteria: Other potential causes of chronic cough and lung disease including cigarette smoking.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Cough. Timepoint: On admission and at the end of week 2,4, 8 and12 of the treatment. Method of measurement: Measurement of severity of cough: normal (0), low (+), moderate (++), and severe (+++).	—

Secondary

Measure	Time frame
Dyspenea. Timepoint: On admission and at the end of week 2,4, 8 and 12 of the treatment. Method of measurement: Measurement of severity: normal (0), low (+), moderate (++), and severe (+++).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mohammad Ali Raeessi

Baqiyatallah University of Medical Sciences

raeessi_ma@yahoo.com+98 21 8803 0514

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026