oral recurrent aphtus ulcer. Stomatitis and related lesions
Conditions
Interventions
Intervention 1: Intervention group: Treatment with probiotic product or probiotic products from Lactobacillus routeri is administered in a gel-sol form, which patients put in the mouth on the lesion a
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: patients with oral aphtus ulcers between 15 -80 years old. patients with oral aphtus ulcers without any systemic medication during last 6 months. patients with one to three oral aphtus ulcers in their mouths Patients with oral lesions that do not have a day off at the beginning of the lesion (the lesion is on the first day of appearance) Patients with oral lesions that do not have a history of rheumatologic disease, GI disease, renal disease, and iron deficiency anemia.
Exclusion criteria
Exclusion criteria: Patients with oral aphtus lesions that have had a lesion more than one day. pregnant patients Patients with diffuse oral lesions and more than 3 concurrent lesions Patients who do not have the opportunity to travel for frequent or repeated examinations.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The size of the lesions in millimeters. Timepoint: determination at 1,3,5 and 7 days. Method of measurement: size determination by ruler.;Severity of burning and pain based on visual analogue score (VAS) (score between 0-10). Timepoint: determination at 1,3,5 and 7 days. Method of measurement: Evaluation by VAS method and numerical expression of pain and burning intensity.;Duration of recovery in terms of number of days. Timepoint: daily check for seven days. Method of measurement: Improvement of clinical symptoms, absence of oral lesions and complete relief of burning and pain. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMostafa Rezaee
Shiraz University of Medical Sciences
Outcome results
None listed