Mucous plugs in mechanically ventilated patients. Other specified respiratory disorders
Conditions
Interventions
Intervention 1: The case group will receive NAC via their nebulizers, 3 times a day for 1 day. A dilution of 3ml of NAC 20% with 7ml saline will be prepared for each episode. Suctioning of the ETT wil
Prevention
Treatment - Drugs
The case group will receive NAC via their nebulizers, 3 times a day for 1 day. A dilution of 3ml of NAC 20% with 7ml saline will be prepared for each episode. Suctioning of the ETT will be done after
The control group will only receive saline via their nebulizers 3 times a day for 1 day.10ml saline will be prepared for each episode. Suctioning of the ETT will be done after each episode and secreti
Sponsors
Shiraz University of Medical Sciences
Eligibility
Sex/Gender
All
Age
15 Years to 90 Years
Inclusion criteria
Inclusion criteria: Inclusion Criteria: Intubated; 72 hours mechanical ventilation. Exclusion criteria: Hemodynamic instability; Tracheostomy; Organophosphate poisoning.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Secretions. Timepoint: 12 hours, 24 hours. Method of measurement: auscultation, suction secretions' weight, volume, and density.;Oxygenation. Timepoint: baseline, 12 hours, 24 hours. Method of measurement: Oxygen saturation, tidal volume, auto-PEEP.;Airway resistance. Timepoint: baseline, 12 hours, 24 hours. Method of measurement: plateau and peak pressures. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmir Anushiravani
Shiraz University of Medical Sciences
Outcome results
None listed