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Comparing the effectiveness of pre and post intubation injection of dexamethasone in reducing postoperative sore throat

Comparing the effectiveness of pre and post intubation injection of dexamethasone in reducing postoperative sore throat in patients candidated for ENT surgery with general anesthesia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201104272821N4
Enrollment
70
Registered
2011-06-11
Start date
2011-04-04
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

sore throat. Other complications of surgical and medical care, not elsewhere classified

Interventions

Intervention 1: Group A: 8 mg intravenous Dexametasone 30 minutes before intubation. Intervention 2: Group B: 8 mg intravenous Dexametasone 30 minutes after intubation.
Treatment - Drugs
Group A: 8 mg intravenous Dexametasone 30 minutes before intubation
Group B: 8 mg intravenous Dexametasone 30 minutes after intubation

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
30 Years to 60 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: all patients with ENT disease that need to surgery, age between 30-60 years old. Exclusion criteria: surgery for throat and larynx (tonsils and vocal nodules), upper respiratory infections or sore throat, use of steroid or anti-pain drugs before surgery, change of head position during surgery, patients with NG tube, intubation less than 60 or more than 300 minutes, vomiting during study.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Sore throat. Timepoint: 24 hours. Method of measurement: 4-point scale table.

Secondary

MeasureTime frame
Severity of pain. Timepoint: 24 hours. Method of measurement: Visual Analogue scale.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactParisa Sadeghian

Tabriz University of Medical Sciences

pink.blossom@yahoo.com+98 41 1334 7054

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026