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Effect of Clove extract mouthwash on incidence of Ventilator-Associated Pneumonia

Effect of Clove extract mouthwash on incidence of Ventilator Associated Pneumonia in hospitalized patient in critical care unit

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110427006318N13
Enrollment
10
Registered
2020-10-11
Start date
2020-10-26
Completion date
Unknown
Last updated
2020-11-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ventilator-Associated Pneumonia. Pneumonitis due to food and vomit

Interventions

Intervention 1: Intervention group: In the intervention group, mouthwash by 15 ml of clove extract, with concentration 33% from 20% solution, prepared from Dr. Jahangir company, are doing twice a day

Sponsors

Semnan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: New patient admitted to the intensive care unit Age over 18 years Patients under mechanical ventilation for more than 48 hours No aspiration symptoms or pneumonia No infection with Covid-19 No contraindications to oral care No contraindication to elevation of head of bed at least 30 degrees Insensitivity to chlorhexidine 0.2%

Exclusion criteria

Exclusion criteria: Fever 38.5 and above during the first 24 hours after intubation Positive PCR test (infection of Covid-19) Re-intubation more than 3 times Apache II score above 30

Design outcomes

Primary

MeasureTime frame
Ventilator-Associated Pneumonia. Timepoint: 1th and 5th days. Method of measurement: The assessment tool of ventilator-associated pneumonia modified clinical pulmonary infection score, which according to the body temperature, the white blood cell count, tracheal secretions, Ratio of arterial oxygen pressure to inspired oxygen fraction and chest x ray diagnose pneumonia.

Secondary

MeasureTime frame
Ventilator-Associated Pneumonia. Timepoint: 1th and 5th days. Method of measurement: The assessment tool of ventilator-associated pneumonia modified clinical pulmonary infection score, which according to the body temperature, the white blood cell count, tracheal secretions, Ratio of arterial oxygen pressure to inspired oxygen fraction and chest x ray diagnose pneumonia.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMonir Nobahar

Semnan University of Medical Sciences

nobahar43@semums.ac.ir+98 23 3365 4190

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026