Effect of Tranexamic acid reduces bleeding during surgery

Effect of Tranexamic acid to reduce bleeding during surgery on fracture of femoral shaft aged in 20-50 year

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104256280N1

Enrollment

Registered

2014-04-30

Start date

2014-07-16

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femur fractures. Fractures of other parts of femur

Interventions

Intervention 1: Interval I )Tranexamic acid 15 mg kg infusion for 10 minutes. Intervention 2: Intervention 2) saline for 10 minutes.

Treatment - Drugs

Placebo

Interval I )Tranexamic acid 15 mg kg infusion for 10 minutes

Intervention 2) saline for 10 minutes

Eligibility

Sex/Gender

All

Age

20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: lateral fractures of the femoral shaft without any comminuted; no evidence of Ischemic, Heart disease or history of any treatment of Heart disease before the operation; anticoagulant medications were not taken before surgery; they didn't have any evidence of brain trauma or history of stay in intensive care unit (ICU) caused by brain disease, also there weren't evidence of Ischemic or hemorrhagic stroke including (SAH) subarachnoid hemorrhage of disease. Exclusion criterion: surgery takes time more than 90 minutes.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Hemoglobin. Timepoint: Four hours before and after surgery up to 24 hours. Method of measurement: g/dl,Cell counter Sysmex KX-21.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Haghighi

Guilan University of Medical Sciences

mohaghighi@gums.ac.ir; arcguilan1392@gmail.com+98 13 1321 0424

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026