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Comparison of Ketamine, Tramadol, and Ondansetron in shiver controlling

Comparison of the effectiveness of Ketamine, Tramadol and Ondansetron on prevention of shivering due to Spinal Anesthesia in cesarean section surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110425006281N2
Enrollment
508
Registered
2018-12-29
Start date
2018-11-22
Completion date
Unknown
Last updated
2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Shivering Complication in Spinal Anesthesia in Cesarean Section. Other complications of spinal and epidural anesthesia during labor and delivery

Interventions

Intervention 1: Intervention group: low dose of ketamine (0.2 milligrams per Kilogram intravenous), (500 milligrams per 10 milliliters of the Stroup pharmaceutical company in Belgium). Immediately aft

Sponsors

Rasht University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 39 Years

Inclusion criteria

Inclusion criteria: Pregnant women Candidates for cesarean section Under spinal anesthesia ASA class I, II Age between 18-39

Exclusion criteria

Exclusion criteria: History of allergy Prohibition for each of the studied drugs Addiction to any chemical or natural compound Psychosis Having cold Heart disease Liver and kidney dysfunction History of seizure History of using Monoamine Oxidase inhibitor in the past 14 days Severe asthma Respiratory depression The initial temperature of the patient`s body is above 38 Celsius or the central temperature is less than 36 Celsius Getting any medication that changes the thermoregulation Weight over 100 Kilograms and below 50 Kilograms History of using vasodilator Cases requiring sedation or having intravenous administration due to partial spinal anesthetics A condition that temperature cannot be maintained due to equipment problems in heating and cooling systems

Design outcomes

Primary

MeasureTime frame
Severity of shivering. Timepoint: Every 5 minutes during surgery and every 15 minutes in 45 minutes of recovery time, the intensity of shivering will be recorded. Method of measurement: Shivering classification table.;Baby`s Apgar Minute One and five. Timepoint: Minute one and five of baby's birth. Method of measurement: Based on Apgar Assessment Table.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Ali Mohammadzadeh Joryabi

Rasht University of Medical Sciences

alimj1393@gmail.com+98 13 3366 9066

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026