Efficacy and safety of two muscle relaxants cisatracurium and succinylcholine in Electroconvulsive therapy

Comparison of efficacy and safety of two muscle relaxants cisatracurium and succinylcholine in Electroconvulsive therapy; A randomized, single-blind clinical trial study

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110425006280N14

Enrollment

Registered

2023-06-11

Start date

2023-06-22

Completion date

Unknown

Last updated

2023-06-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Investigation of using cisatracurium instead of succinylcholine for anesthesia in electroshock therapy in cases that there is a contraindication for succinylcholine. Other complications of anesthesia

Interventions

Intervention 1: first intervention group: Before receiving anesthesia and electroshock therapy, standard monitoring of non-invasive blood pressure, pulse oximetry, electrocardiogram, and end-tidal car

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients 18 years and older ASA I,II Normal body mass index No criteria for difficult mask ventilation No contraindication for cisatracurium and succinylcholine

Exclusion criteria

Exclusion criteria: myasthenia gravis History of malignant hyperthermia History of burns Kidney failure Guillain-Barré syndrome Any nerve denervation Dangerous arrhythmias

Design outcomes

Primary

Measure	Time frame
Seizure duration. Timepoint: Momentary monitoring of colonic movements in the organ from the beginning of the seizure. Method of measurement: chronometer.;Time of returning of the effective breaths of the patient. Timepoint: Momentary monitoring from the beginning of the seizure. Method of measurement: chronometer.;Time of recovery. Timepoint: recovery time. Method of measurement: Observation.;Patient discharge from recovery. Timepoint: Momentary monitoring to score 9 or 10. Method of measurement: Aldret score.	—

Measure

Time frame

Seizure duration. Timepoint: Momentary monitoring of colonic movements in the organ from the beginning of the seizure. Method of measurement: chronometer.;Time of returning of the effective breaths of the patient. Timepoint: Momentary monitoring from the beginning of the seizure. Method of measurement: chronometer.;Time of recovery. Timepoint: recovery time. Method of measurement: Observation.;Patient discharge from recovery. Timepoint: Momentary monitoring to score 9 or 10. Method of measurement: Aldret score.

—

Secondary

Measure	Time frame
Mean arterial blood pressure (MAP). Timepoint: Before injection, 1 minute after seizure and 15 minutes after induction of anesthesia. Method of measurement: Blood pressure measurement.;Heart rate (pulse/ minute). Timepoint: Before injection, 1 minute after seizure and 15 minutes after induction of anesthesia. Method of measurement: Heart rate monitor.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad Haghighi

Rasht University of Medical Sciences

manesthesist@gmail.com+98 13 3211 1319

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026