Skip to content

Target Controlled Infusion of Remifentanil with Propofol or Desflurane under Bispectral Index Guidence: quality of anesthesia and recovery profile

Target Controlled Infusion of Remifentanil with Propofol or Desflurane under Bispectral Index Guidence: quality of anesthesia and recovery profile

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT201104236266N1
Enrollment
40
Registered
2011-05-09
Start date
2009-04-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Quality of anesthesia and recovery profile. Other and unspecified general anaesthetics

Interventions

Intervention 1: TCI geoup
general anaesthesia will be induced with 3 ng mL-1 and 4 µg mL-1 effect site concentrations (Ce) of remifentanil and propofol. Intervention 2: DES group
general anaesthesia will be induced with 3 ng mL-1 and 4 µg mL-1 effect site concentrations (Ce) of remifentanil and propofol, respectively, after intubation, propofol infusion is ceased in the DES gr
Treatment - Drugs
TCI geoup
general anaesthesia will be induced with 3 ng mL-1 and 4 µg mL-1 effect site concentrations (Ce) of remifentanil and propofol

Sponsors

none
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patients aged 18-65 who are candidate for ENT procedures Exclusion criteria: Taking any sedative or analgesic drugs 24 hours before surgery, significantly hypertensive (diastolic blood pressure less than100 mmHg) or hypotensive (systolic blood pressure less 100 mmHg) and presence the signs of bradyarrhythmic heart disorders

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure. Timepoint: During anesthesia. Method of measurement: Equipment.

Secondary

MeasureTime frame
Heart rate. Timepoint: During anesthesia. Method of measurement: Physical exam.;Early emergence from anesthesia. Timepoint: During anesthesia. Method of measurement: Physical exam.;Patients’ aldrete score (ARS). Timepoint: During anesthesia. Method of measurement: Physical exam.

Countries

Turkey

Contacts

Public ContactAhmet Mahli

Gazi University Faculty of Medicine, Department of Anaesthesiology and Reanimation

amahli@gazi.edu.tr+90 312 2024166

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026