Comparison the effect of intranasal midazolam versus different doses of intranasal ketamine in reducing preoperative pediatric anxiety

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104236254N1

Enrollment

120

Registered

2011-09-07

Start date

2010-05-23

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Behavioural and emotional disorders with onset usually occurring in childhood and adolescence. Phobic anxiety disorder of childhood

Interventions

Intervention 1: Control : Group3 received 1 drop/kg normal salin. Intervention 2: Intervention: patients in group one received0.2 mg/kg midazolam. Intervention 3: Intervention: group 2 received0.5 m

Prevention

Control : Group3 received 1 drop/kg normal salin

Intervention: patients in group one received0.2 mg/kg midazolam

Intervention: group 2 received0.5 mg/kg ketamine

Intervention: group 4received3 mg/kg ketamine

Eligibility

Sex/Gender

All

Age

2 Years to 8 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Elective surgery ;ASA class 1; Age between 2-8 years Exclusion criteria : ASA class 2 or higher ;Children using antihistaminic, anticonvulsive ,analgesic or sedative agents ;Children with nasopharyngeal disorder, upper respiratory tract infection ,epistaxis or allergic rhinitis.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anxiety. Timepoint: Fftheen minutes after drug usage(before IV line insertion). Method of measurement: M-Yale PAS.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNematollah Adeli

Qazvin, University of Medical Science and health services

neadeli@qums.ac.ir+98 28 1223 6381

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026