Hyperemesis gravidarum. Excessive vomiting in pregnancy
Conditions
Interventions
Intervention 1: group I (control): Prednisone 5 mg as capsule, three times daily for a week. In the second week in both treatment groups every three days decreased capsule gradually treatment was stop
Treatment - Drugs
group I (control): Prednisone 5 mg as capsule, three times daily for a week. In the second week in both treatment groups every three days decreased capsule gradually treatment was stopped in the secon
group II (case): Promethazine 25 mg as capsule three times daily for a week. In the second week in both treatment groups every three days decreased capsule gradually treatment was stopped in the secon
Sponsors
Vice Chancellor for Research and Technology
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Women 18 to 35 years, First or second pregnancy, Less than 16 weeks gestational age according to last menstrual period and ultrasound, Vomiting more than three times a day with no response to outpatient treatment, Weight loss over 3 kg and a positive urine ketone. Exclusion criteria: Concurrent Medical diseases, Anti-emetic drugs with in three days, Hydatid form mole, Twin pregnancy and iron supplementation.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of nausea and vomiting. Timepoint: The first day, second, third, fourth, 14th (end of treatment) and 28th (two weeks after treatment). Method of measurement: Visual Analoge Scale and the number of vomiting per day. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNargess Gholizadeh Pasha
Fatemehzahra Fertility & reproductive Health Research Center
Outcome results
None listed