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The comparison of the effect of Dextromethorphan with Placebo on postoperative pain in adenotonsillectomy

The comparison of the effect of Dextromethorphan with Placebo on postoperative pain in adenotonsillectomy

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT201104226252N1
Enrollment
160
Registered
2011-06-30
Start date
2011-06-14
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Intensity of Pain. Symptoms and signs involving appearance and behaviour

Interventions

Intervention 1: 5ml of decstrometorphan 2 h before and after operation every 6 h till 24h. Intervention 2: Placebo 2h before and after operation every 6h till 24h.
Treatment - Drugs
Placebo
5ml of decstrometorphan 2 h before and after operation every 6 h till 24h
Placebo 2h before and after operation every 6h till 24h

Sponsors

Shahrekord University of Medical Sciences, Vice chancellory for research
Lead Sponsor

Eligibility

Sex/Gender
All
Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: children with 3-12 years old, undergoing surgery for adenotonsilectomy, not having background on bloodshed disease, non addicted parents, not using walnuts and nuts in 10 recent days, not being prohibited from public operation, not having allergy to drugs Exclusion criteria: severe bloodshed during operation, operation takes time more than 30 min, Laryngospasm during extubation, need to a second operation, bloodshed of the operation area after operation, post operation breathing problem

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Pain intensity. Timepoint: before and after interval. Method of measurement: visual scale af pain.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHossein Madineh

Shahrekord University of Medical Sciense

hosseinmadineh@gmail.com+98 38 1222 0016

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026