Skip to content

Comparison of the effect of Carvacrol gel, and Chlorhexidine in reducing pain, and dry socket

Comparison of the effect of Carvacrol gel, and Chlorhexidine in reducing postoperative pain, and dry socket after surgical removal of impacted mandibular third molars- a clinical trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110420006239N4
Enrollment
80
Registered
2021-08-03
Start date
2021-09-23
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Pain. Condition 2: Dry socket. Condition 3: Total analgesic drug consumption. Pain, unspecified Other nonsteroidal anti-inflammatory drugs [NSAID]

Interventions

Intervention 1: Control group: do not receive any kind of mouthwash. Intervention 2: Intervention group I: Rinse once with 0.2%chlorhexidine mouthwash pre-operatively. Intervention 3: Intervention gro

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: All adult patients (over 18 years old) healthy without any systemic disease Absent history of dry socket Having one or two impacted wisdom teeth (surgery on one side only) The presence of adjacent second molars No antibiotics and anti-inflammatory intake at least 7 days before surgery)

Exclusion criteria

Exclusion criteria: Hypersensitivity to local anesthetics History of smoking

Design outcomes

Primary

MeasureTime frame
Pain. Timepoint: The first, second and seventh days after surgery. Method of measurement: Visual analog scale (asking from patient, scoring from 1 to 10).;Dry socket. Timepoint: Seventh day post-operation. Method of measurement: Intraoral examination for signs of dry socket.

Secondary

MeasureTime frame
Number of pain relief tablets taken. Timepoint: The first, second and seventh days after surgery. Method of measurement: Asking the patient.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJavad Yazdani

Tabriz University of Medical Sciences

Yazdanij@tbzmed.ac.ir+98 41 3336 6965

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026