The impact of chemotherapy on ovarian reserve in patients with molar pregnancy

Effects of chemotherapy on anti-mullerian hormone levels in patients with GTN

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104165810N2

Enrollment

Registered

2017-05-09

Start date

2014-01-21

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Hydatidiform mole. Condition 2: molar pregnancy. Neoplasm of uncertain or unknown behaviour: Placenta Hydatidiform mole, unspecified

Interventions

Intervention 1: Intervention group 1: suction curettage, prescription of chemotherapy drugs. Based on the patient's condition, we used MTX or ACD or a combination of both. MTX dosage was 1mg/kg and ad

Diagnosis

Intervention group 1: suction curettage, prescription of chemotherapy drugs. Based on the patient's condition, we used MTX or ACD or a combination of both. MTX dosage was 1mg/kg and administered every

Intervention group 2: Suction Curettage

Eligibility

Sex/Gender

Female

Age

18 Years to 45 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Patient between the ages of 18-45 years who confirmed the molar pregnancy with pathology exclusion criteria: 1- Endocrine diseases 2- History of ovarian surgery

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Anti mullerian hormone. Timepoint: before suction curttage- after zero beta titrage. Method of measurement: ELISA.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactNazanin Atrvash

Hamedan university of medical science

atrvash.nazanin@gmail.com+98 81 3821 3994

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026