Condition 1: Constipation. Condition 2: Cholesterol and lipid metabolism. Condition 3: ?Elevated blood glucose. Condition 4: BMI. Constipation Disorders of bile acid and cholesterol metabolism Elevated blood glucose level Body mass index [BMI]
Conditions
Interventions
Intervention 1: Intervention 2: 10 grams of psyllium mixed in cookies twice per day for 12 weeks. Kamvar Co., Isfahan, Iran. Intervention 2: Intervention 1:10 grams of faxseed mixed in cookies twice p
Treatment - Drugs
Placebo
Intervention 2: 10 grams of psyllium mixed in cookies twice per day for 12 weeks. Kamvar Co., Isfahan, Iran
Intervention 1:10 grams of faxseed mixed in cookies twice per day for 12 weeks. Kamvar Co., Isfahan, Iran
Control group: Participants in the control group will be received psyllium, falxseed and sugar-free orange-flavored maltodextrin cookies for 12 weeks as placebo. Kamvar Co., Isfahan, Iran
Sponsors
Esfahan University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to 75 Years
Inclusion criteria
Inclusion criteria: Patients were included if they had type 2 diabetes. A bowel movement frequency of < 3/week during the past three months.
Exclusion criteria
Exclusion criteria: Patients were excluded from the study if they had weight loss, rectal bleeding abdominal pain history of opioid use in the last 48 h pre-existing severe cardiac endocrinological hematological hepatic renal metabolic neurological or psychiatric disorders Pregnant or nursing women will be excluded Non-compliant patients during baseline or treatment phases as evaluated by taking <75% of either of the test articles during a one-week period throughout the course of the study will be excluded from the evaluable patient data analysis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Constipation intensity. Timepoint: Beginning, 4, 8, 12 week after intervention. Method of measurement: ROME III.;Body weight. Timepoint: Beginning, 4, 8, 12 week after intervention. Method of measurement: Body mass index and body weight.;Lipids . Timepoint: Beginning, 4, 8, 12 week after intervention. Method of measurement: Routine measurement of total cholesterol, triglyceride, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol,.;Fasting plasma glucose . Timepoint: Beginning, 4, 8, 12 week after intervention. Method of measurement: Oxidase method. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNoreddin Soltanian
Isfahan Endocrin and Metabolism Research Center
Outcome results
None listed