Comparative efficacy of probiotic yoghurt and clindamycin in the treatment of bacterial vaginosis in pregnant women in the third trimester

Assessment of the therapeutic effects of probiotic yougurt in comparison with clindamycin in the treatment of bacterial vaginosis in patients in the third trimester of pregnancy referring to prenatal clinic of Imam hospital

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104136183N1

Enrollment

300

Registered

2011-04-23

Start date

2009-08-10

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute vaginitis. Acute vaginitis

Interventions

Intervention 1: Intervention: probiotic yoghurt (100 gram twice a day for one week). Intervention 2: Control: orally-administered clindamycin (300 mg twice a day for one week).

Treatment - Other

Treatment - Drugs

Intervention: probiotic yoghurt (100 gram twice a day for one week)

Control: orally-administered clindamycin (300 mg twice a day for one week).

Eligibility

Sex/Gender

Female

Age

16 Years to 44 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: women in second or third trimester of pregnancy who had bacterial vaginosis according to the presence of minimally three Amsel Criteria, willing to participate Exclusion criteria: having a positive history of background disease, positive urine culture, having a positive history of preterm labor and premature rupture of the membranes, other vaginal infections

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Bacterial vaginosis. Timepoint: before and after intervention. Method of measurement: turnessel paper.	—

Secondary

Measure	Time frame
Preterm labor. Timepoint: before 37 weeks gestational age. Method of measurement: diagnosis of gynecologist.;Preterm rupture of membranes. Timepoint: before 37 weeks of gestational age. Method of measurement: diagnosis of a gynecologist.;Update: June 30, 2011; Recurrence Rate. Timepoint: -. Method of measurement: -.;Update June 30, 2011; PH Level. Timepoint: -. Method of measurement: -.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFateme Golshahi

Tehran Univ of medical sciences

golshahi@razi.tums.ac.ir+98 21 6695 2690

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026