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Buspirone in ADHD

Buspirone versus Methylphenidate in 6-16 aged children with Attention Deficit/Hyperactive Disorder(ADHD). A crossover study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201104116168N1
Enrollment
40
Registered
2011-06-12
Start date
2010-09-11
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Attention Deficit Hyperactivity Disorder. Disturbance of activity and attention

Interventions

Intervention 1: Intervention 1: buspirone was initiated with 0/5 mg/kg/day to maximum 45mg/day. Intervention 2: Intervention 2: Methylphenidate was initiated with 0/5-1 mg/kg/day and adjusted to maxim
Treatment - Drugs
Intervention 1: buspirone was initiated with 0/5 mg/kg/day to maximum 45mg/day.
Intervention 2: Methylphenidate was initiated with 0/5-1 mg/kg/day and adjusted to maximum 60 mg per day

Sponsors

Neuroscience Research Center Kerman University of Medical Sciences, Kerman ,Iran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 16 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: ADHD diagnosis according to DSM-IV-TR criteria that scored above 20 in ADHD-Rating Scale. Exclusion criteria: evidence of a mental retardation(IQ<70) or a major psychiatric problem other than oppositional defiant disorder and conduct disorder or receiving any psychotropic medication through 2 weeks before initiating treatment; medical disorders that would preclude the safe use of methylphenidate or buspirone.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Hyperactivity, impulsivity and inattention symptoms according to parent and teacher point of view. Timepoint: every 2 weeks. Method of measurement: ADHD Rating Scale(parent and teacher form).

Secondary

MeasureTime frame
Side effects include increase or decrease of appetite,weight and sleep,tic,stomachach. Timepoint: every 2 weeks. Method of measurement: Checklist of each drug side effects.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Mahin Eslami Sharbabaki

Kerman University of Medical Sciences

mahineslami@yahoo.com m_eslami@kmu.ac.ir+98 34 1211 6328

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026