migraine without aura. Migraine without aura [common migraine]
Conditions
Interventions
Sodium Valproate 400 mg single dose diluted in 100 cc Normal Saline infusion over 10 minutes
Intervention 1: Single dose 10 mg intramuscular Metoclopramide injection followed 10 minutes later by single dose 6 mg subcutaneous Sumatriptan injection. Intervention 2: Sodium Valproate 400 mg s
Treatment - Drugs
Single dose 10 mg intramuscular Metoclopramide injection followed 10 minutes later by single dose 6 mg subcutaneous Sumatriptan injection
Sponsors
Guilan University of Medical Science, Vice chancellor for research
Eligibility
Sex/Gender
All
Age
16 Years to 70 Years
Inclusion criteria
Inclusion criteria: inclusion criteria include :fulfilling international headache society criteria for migraine without aura; absence of cardiovascular disease; absence of cerebrovascular disease; absence of drug allergy; absence of pregnancy; age between 16 to70 year-old. Exclusion criteria include :occurrence of serious adverse drug effects at any time during drug administration.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Headache severity. Timepoint: before treatment,after 2, 4 , and 24 hours. Method of measurement: visual analog scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects profile. Timepoint: before treatment ,after 2 , 4, and 24 hours. Method of measurement: history taking and physical examination. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Hamidreza Hatamian
Poorsina hospital of Rasht, Guilan University of Medical Sciences
Outcome results
None listed