Infertility. Female infertility associated with anovulation
Conditions
Interventions
Intervention 1: Group A received clomiphene 50 mg up to 150mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and durati
Treatment - Drugs
Group A received clomiphene 50 mg up to 150mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and duration to achieve ma
Group B received tamoxifen 10 mg up to 30mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and duration to achieve matu
Group C received letrozole 2.5 mg up to 7.5mg for 5-7days. Treatment starded with minimum dose and effect of drug monitored by sonography. Drugs have been increased in dose and duration to achieve ma
Sponsors
Kordestan University of Medical Sciences and Health Services
Eligibility
Sex/Gender
Female
Age
15 Years to 40 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: women between 15 to 40 years old with infertility due to unovulation who refer to gynecologists, and they have normal semen analysis, hystrosalpingography and evidence of unovulation (include irregular menses and less than 14 mm folicle in sonography) Exclusion criteria: Abnormal gondothrpins (LH, FSH) and prolactin, clinical finding of hyperandrogenism (including acne and hirsutism) and poly cystic appearance in sonography (including ovarian enlargement and subcoticular multiple small cysts)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ovulation. Timepoint: monthly. Method of measurement: sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| Live Birth. Timepoint: after delivery. Method of measurement: postpartum period.;Pregnancy. Timepoint: after missed period. Method of measurement: serum BHCG measurment.;Abortion. Timepoint: monthly in first half of pregnancy. Method of measurement: sonography.;Twin Pregnancy. Timepoint: first prenatal care. Method of measurement: sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFariba Seyedoshohadaei MD
Besat Hospital -Kurdistan University of Medical Sciences
Outcome results
None listed