Comparasion of therapiutic effects of oral Erythromycin along with low dose oral Isotretinoin and oral Erythromycin and low dose Flutamide versus Doxycyclin in female severe acne vulgaris.

Comparasion therapiutic effects of oral Erythromycin along with low dose oral Isotretinoin and oral Erythromycin and low dose Flutamide versus Doxycyclin in female severe acne vulgaris .

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104094310N6

Enrollment

Registered

2014-04-19

Start date

2013-09-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Intervention 1: Control group received 100 ml oral daxycycline every 12 hours during 2 mounths. Intervention 2: First intervention group(the group that received oral eritromycin and oral isotretinoin

Treatment - Drugs

Control group received 100 ml oral daxycycline every 12 hours during 2 mounths.

First intervention group(the group that received oral eritromycin and oral isotretinoin ),this group received 800 ml of oral eritromycin (400 ml/BID) and 20 ml oral isotretinoin every 48 hours during

Second intervention group received 800 ml oral eritromycin a day (400 ml/BID) and 65 ml oral flutamid a day during 2 mounth.

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criterion: females with severe acne. Exclusion criteria: pregnancy; breastfeeding; liver disease; hyperlipidemia; receiving anti acne drugs; OCP pills; spironolacton in last 2 months.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Decrease of acne leasions. Timepoint: Onset of study & 30th & 60th day's of study. Method of measurement: Observation.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Ghasem Golmohammadi

Ardabil University of Medical Sciences

m.golmohammadi@arums.ac.ir+98 45 1551 0060

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026