Effects of combined treatment of Doxycycline dual with flutamide in female severe acne

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104084310N5

Enrollment

Registered

2014-04-28

Start date

2013-04-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acne vulgaris. Acne vulgaris

Interventions

Oral flutamide 125 mg/day dual with Doxycycline 100 mg/day and topical clindamicine 1% for six months.

Treatment - Drugs

Oral flutamide 125 mg/day dual with Doxycycline 100 mg/day and topical clindamicine 1% for six months

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criterion: females with severe acne. Exclusion criteria: liver disease; pregnancy and breastfeeding; receiving anti acne drug's, OCP and spironolacton in last 2 months.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Decrease in acne leasions. Timepoint: Every two months. Method of measurement: lesions counting.	—

Secondary

Measure	Time frame
Patients`satisfaction. Timepoint: Every two months. Method of measurement: Questionnaire.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactGolmohammadi . Ghasem

Ardabil University of Medical Science

m.golmohammadi@arums.ac.ir+98 45 1551 0060

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026