Comparision of the preemptive effect of Ketorolac (IV) versus Pethidine on shivering and pain after cesarean section under spinal anesthesia

Comparision of the preemptive effect of Ketorolac (IV) versus Meperidine on shivering and pain after cesarean section under spinal anesthesia

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT201104073051N4

Enrollment

150

Registered

2016-04-24

Start date

2015-02-20

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Complications predominantly related to the puerperium. Other complications of spinal and epidural anaesthesia during the puerperium

Interventions

First group received 50 mg intravenous Meperidine

Intervention 1: First group received 50 mg intravenous Meperidine. Intervention 2: Second group received 30 mg intravenous Ketorolac. Intervention 3: Third group received 2 CC intravenous Normal sali

Treatment - Drugs

Second group received 30 mg intravenous Ketorolac

Third group received 2 CC intravenous Normal saline

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Inclusion criteria: Pregnant women who candidate for elective cesarean section; ASA class 1,2. Exclusion criteria: History of asthma? peptic ulcer? renal? hepatic or hemorrhagic disease? Consumption or history of sensitivity reaction to opioid? NSAIDs or other analgesics and MAOIs.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Shivering. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: Vision and medical records.;Pain. Timepoint: Until 24 hours post operation. Method of measurement: VAS (Visual Analogue Scale).	—

Secondary

Measure	Time frame
Temperature. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: Thermometriy from tympanic membrane.;Blood pressure. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: With manometriy from brachial artery.;Pulse rate. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: With monitoring.	—

Measure

Time frame

Temperature. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: Thermometriy from tympanic membrane.;Blood pressure. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: With manometriy from brachial artery.;Pulse rate. Timepoint: 10 minute before anesthesia, end of surgery and every 30 minute until an hour. Method of measurement: With monitoring.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Maryam Alsadat Mosallaei

Qazvin University of Medical Sciences

m.mosallaei93@gmail.com+98 28 3333 6001

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026