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The effect of gabapentin in controlling the nausea and vomiting after the laparoscopic cholecystectomy surgery

The effect of gabapentin in controlling the nausea and vomiting after the laparoscopic cholecystectomy surgery

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201104042080N5
Enrollment
105
Registered
2011-07-22
Start date
2010-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

laparoscopic cholecystectomy. Cholelithiasis

Interventions

Intervention 1: Gabapentin tablet (300 mg) is given to the patient 1 hour before the surgery orally with 100 cc water. Intervention 2: Gabapentin (600 mg) is given to the patient 1 hour before the sur
Prevention
Placebo
Gabapentin tablet (300 mg) is given to the patient 1 hour before the surgery orally with 100 cc water.
Gabapentin (600 mg) is given to the patient 1 hour before the surgery orally with 100 CC water.
The placebo tablet is given to the patient 1 hour before the surgery orally with 100 cc water.

Sponsors

Arak university of medical sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: the age group of 20-60 years. Exclusion criteria: history of using analgesic and narcotic prior to the surgery; history of chronic lung and heart diseases; history of using corticosteroid; movement disorders; history of smoking; patient who use Gabapentin; history of allergy to gabapentin; people who need N.G tube after exiting the surgery room.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Nausea. Timepoint: Each 2hour. Method of measurement: Chek list and physical examination and VAS score.;Vomiting. Timepoint: Each 2 hours. Method of measurement: Chek list and physical examination.

Secondary

MeasureTime frame
Motion sickness. Timepoint: Each 2 hours. Method of measurement: Chek list and physical examination.;Confiusion. Timepoint: Each 2 hours. Method of measurement: Chek list and physical examination.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Afsaneh Norouzi

Arak university of medical sciences

norouzi.a@arakmu.ac.ir+98 86 1222 4790

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026