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Effects of anesthetics on stapedius reflex

Comparison of propofol-remifentanil and sevoflurane effects on stapedius reflex in children undergoing cochlear implant surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201104026022N3
Enrollment
36
Registered
2011-05-07
Start date
2011-05-01
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesia. Anaesthetics and therapeutic gases

Interventions

Intervention 1: Intervention group will receive remifentanil (0.2-0.5mcg/kg/min) + propofol (100-150mcg/kg/min) during 4 hours anesthesia. Intervention 2: Control group will receive 2-3% MAC sevoflura
Treatment - Drugs
Intervention group will receive remifentanil (0.2-0.5mcg/kg/min) + propofol (100-150mcg/kg/min) during 4 hours anesthesia
Control group will receive 2-3% MAC sevoflurane through the ventilator, during 4 hours anesthesia

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
No minimum to 7 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: Children with severe to profound sensory neural hearing loss who are candidate for cochlear implant surgery Exclusion criteria: Children with a history of adverse reaction to any study drug

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Stapedius reflex. Timepoint: evaluation is done while testing. Method of measurement: by Nucleus Freedom cochlear implant divice.

Secondary

MeasureTime frame
Hemodynamic changes. Timepoint: every 10 minutes during anesthesia. Method of measurement: by electrocardiography and blood pressure measurment.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Taheri

Children hospital of Tabriz

dr.reza.taheri@gmail.com+98 41 1526 2250

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026