Effect of Dexmedetomidine- Fentanil on postoperative pain of spine surgery

The effect of adding Dexmedetomidine to fentanyl for pain management after spinal fusion surgery using intravenous patient controlled analgesia pumps

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20110402006115N4

Enrollment

Registered

2018-12-31

Start date

2018-03-21

Completion date

Unknown

Last updated

2019-01-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

spinal surgery.

Interventions

Intervention 1: Intervention group: dexmedetomidine 0.5 mcg/kg + fentanyl 0.5 mcg/kg in PCA infusion pump for 24 hours after surgery. The required amount is calculated separately for each patient. Int

Eligibility

Sex/Gender

All

Age

20 Years to 70 Years

Inclusion criteria

Inclusion criteria: The candidate for the posterior fusion of the lower back and the thoracic spine Age range 20 to 70 years Patients ASA 1 or 2 Satisfaction to participate in the study Educable and have the ability to cooperate

Exclusion criteria

Exclusion criteria: History of acute allergic reaction to Dexmedetomidine or Fentanil Patients with mental and physical disabilities in the application of pain pumps The presence of any moderate to severe CVD and respiratory instability

Design outcomes

Primary

Measure	Time frame
Pain score base on VAS criteria. Timepoint: Start logging in to recovery, every hour to 24 hours. Method of measurement: VAS CRITERIA SCORE.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Mojtaba Rahimi

Esfahan University of Medical Sciences

rahimi@med.mui.ac.ir+98 31 3235 0004

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026