Hot flash. Menopausal and female climacteric states
Conditions
Interventions
Intervention 1: Licorice capsules contained 330mg licorice root abstract.The subjects took them for 8 weeks 3 times a day (morning, noon and night). Intervention 2: Placebo capsules had 330mg starch
Treatment - Drugs
Placebo
Licorice capsules contained 330mg licorice root abstract.The subjects took them for 8 weeks 3 times a day (morning, noon and night).
Placebo capsules had 330mg starch with the same shape. The subjects in control group took them for 8 weeks 3 times a day (morning, noon and night).
Sponsors
Sbmu Pharmaceutical Sciences Research Center
Eligibility
Sex/Gender
Female
Age
45 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: The subjects were between 45-60, had body mass index (BMI) under 29, experienced amenorrhea at least 1 year or at most 3 years, suffered from hot flash and used no drug or hormone to relieve it. In addition, they had no known disease in their medical records, didn’t take antidepressants or sedatives, were married or lost their husbands not sooner than 1 year, experienced no stressful event (e.g. death of close family members, divorce etc.) in the past 6 months, were not vegetarian or had no allergy to herbs as well as no history of estrogenic cancers in themselves or their close relatives. Exclusion criteria: The subjects were decided to use drug or hormone and herbals medicin to relieve hot flashes.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Severity of hot flash. Timepoint: At the end of each week, for 2 weeks before the intervention , for 8 weeks of the intervention for 4 weeks of followed up stage. Method of measurement: Information form.;Relief. Timepoint: Weekly. Method of measurement: Information form.;Recurrence. Timepoint: Weekly. Method of measurement: Information form.;Frequency of hot flash. Timepoint: At the end of each week, for 2 weeks before the intervention , for 8 weeks of the intervention for 4 weeks of followed up stage. Method of measurement: Information form. | — |
Secondary
| Measure | Time frame |
|---|---|
| Daily food intake. Timepoint: At the end of each week. Method of measurement: Information form.;Blood pressure. Timepoint: Weekly. Method of measurement: Sphygmomanometer( instrument for measuring blood pressure).;Weight. Timepoint: Weekly. Method of measurement: Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Nahidi
Shaheed Beheshti University of Medical Sciences and Health Services
Outcome results
None listed