Condition 1: ?Effect of tramadol on post tonsillectomy pain. Condition 2: Effect of ketamine on the post tonsillectomy pain. Opioids and related analgesics Other and unspecified general anaesthetics
Conditions
Interventions
Intervention 1: Ketamine infiltration in volume 2 cc - 0.5mg / kg, 1 cc into the area the submucousal of anterior fossa and beds of each tonsils after intubation, and three minutes before surgery sta
Prevention
Ketamine infiltration in volume 2 cc - 0.5mg / kg, 1 cc into the area the submucousal of anterior fossa and beds of each tonsils after intubation, and three minutes before surgery starting.
Tramadol infiltration in volume 2 cc - 2mg / kg, 1 cc into the area the submucousal of anterior fossa and beds of each tonsils after intubation, and three minutes before surgery starting.
Normal saline infilttration in volume 2 cc - 1 cc into the area the submucousal of anterior fossa and beds of each tonsils after intubation, and three minutes before surgery starting.
Sponsors
Vice chancellor for research, .... University of shahid sadoughi medical university
Eligibility
Sex/Gender
All
Age
5 Years to 12 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1); 5-12 yr patients, who are candidate for elective bilateral tonsillectomy due to chronic or recurrent tonsillitis ; 2);ASA class =I,II (American society of anesthesiology); 3) ;No evidence of difficult air way management: 4);Without cardio, pulmonary, endocrine, psycho and metabolic disease; 5);Do not use analgesic drugs in the last 24 hours; 6);No electrolyte abnormalities; 7);No tonsillectomy indication except chronic or recurrent tonsillitis; 8);No mental, cerebral and growth problems; 9);No sore throat Exclusion criteria: 1) ;surgery time > 1 hour; 2) ;History of reaction to drugs studies; 3) ;Unexpected problems during anesthesia and surgery (excessive bleeding, difficult intubation,...); 4) ;Cauterization that used during surgery
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-tonsillectomy pain. Timepoint: Each 10 min in the recovery room until 1 hour. Then each 2 hour until 12 hour in the ward. Method of measurement: ;CHEOPS score;. | — |
Secondary
| Measure | Time frame |
|---|---|
| Sedation. Timepoint: 2- 4- 6- 8- 12 hours post interance to ward. Method of measurement: RAMSY score.;Systolic, diastolic, mean blood pressure. Timepoint: Each 5 min during surgery, 5- 10 - 15- 30- 60 min in the recovery. Method of measurement: Non invasive blood pressure.;Negative Behaviors and hallucination. Timepoint: In the recovery room. Method of measurement: Visual.;Heart rate. Timepoint: Each 5 min during surgery, 5- 10 - 15- 30- 60 min in the recovery. Method of measurement: EKG.;Nausea, vomiting. Timepoint: IN the recoverey room until 1 hour and in ward until 12 hours. Method of measurement: Visual and Asking the patient and her or his parents.;Thr first time if needed analgesic. Timepoint: In the recovery and ward. Method of measurement: VAS.;Starting time of fluids. Timepoint: In the ward. Method of measurement: Visual and Asking the patient and her or his parents. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr Vida Ayatollahi
Yazd University of Medical Sciences
Outcome results
None listed