Benign Nodule of Thyroid. Disorders of thyroid gland
Conditions
Interventions
Intervention 1: Intervention group: levothyroxine with the initial dose of 50µg/day (produced by Iran Hormone Company) in which levothyroxine dose was coordinated with TSH serum level after 6 weeks su
Treatment - Drugs
Intervention group: levothyroxine with the initial dose of 50µg/day (produced by Iran Hormone Company) in which levothyroxine dose was coordinated with TSH serum level after 6 weeks suppressive treatm
Control group: no intervention
Sponsors
Bobol University of Medical Siences and Health Services
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: age lower than 60 years old, single thyroid nodule that have benign fine needle aspiration, TSH in normal limit (0.5-4.5 mu/I) Exclusion criteria: age more than 60, history of hypo or hyperthyroidism, neck radiation, history of any cancer, history of thyroid cancer in family, live in another region where the study is performed, history of levothyroxine or other thyroid related drugs, TSH lower or higher than normal, pregnancy, other disease (cardiovascular or hepatic and)
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Size of benign thyroid nodule. Timepoint: Before and 6 months after intervention. Method of measurement: sonography. | — |
Secondary
| Measure | Time frame |
|---|---|
| TSH. Timepoint: Before, 6 weeks and 6 months after the intervention. Method of measurement: labratory kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMohammad Amani
Babol University of Medical Siences and Health Services
Outcome results
None listed