periodontitis. Chronic periodontitis
Conditions
Interventions
one-stage full mouth disinfection.
Treatment - Other
one-stage full mouth disinfection
Sponsors
Hamedan dental faculty
Eligibility
Sex/Gender
All
Age
25 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: 1- patients aged 25 to 70 years 2- Having at least 12 teeth (regardless of third molars, teeth with orthodontic appliances, crowns, bridges and implants) 3- Diagnosis of moderate to advanced chronic periodontitis 4- having informed consent. Exclusion criteria: 1- Patients with a contra-indication for surgery or local anesthesia or scaling 2- Systemic disease (eg diabetes mellitus, cancer, AIDS, metabolic bone disease, diseases that delay the healing pockets, previous radiotherapy or immunosuppressive treatment, autoimmune diseases, allergies, infectious diseases, neutropenia, bleeding disorders, Rheumatoid arthritis, bowel disease, lung disease, multiple sclerosis) 3- pregnancy or lactation 4- History of systemic antibiotics use in the past six months 5- History of continuous use of NSAIDS in the past six months 6- scaling and root planning in the past year 7- contagious diseases 8- History of smoking in the past six months
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum levels of IL-17. Timepoint: 6 weeks later. Method of measurement: laboratory assessment (IL-17 ELISA kit). | — |
Secondary
| Measure | Time frame |
|---|---|
| Serum IL-23 level. Timepoint: 6 weeks later. Method of measurement: laboratory assessment (IL-23 ELISA kit). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Zarandi
Hamedan dental faculty
Outcome results
None listed