poly cystic ovary syndrome. PCOD ( poly cystic ovary syndrome)
Conditions
Interventions
Intervention 1: Intervention: metformin tablet 500 mg TDS from two months before starting ovulation induction, then ovulation induction started on day 2-6 of menstrual cycle with Letrozole 2.5 mg twic
Treatment - Drugs
Intervention: metformin tablet 500 mg TDS from two months before starting ovulation induction, then ovulation induction started on day 2-6 of menstrual cycle with Letrozole 2.5 mg twice per day, when
In control groups: no drug used before starting ovulation induction, then ovulation induction started on day 2-6 of menstrual cycle with Letrozole tablet 2.5 mg twice per day, when dominant follicle
Sponsors
Tehran University of Medical Science and Health Service
Eligibility
Sex/Gender
Female
Age
18 Years to 35 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: Infertile women were included in the patients attending the outpatient clinic of the Infertility Research Centre of Shariati Hospital. The diagnosis of PCOD was based on the Rotterdam criteria, age between 18 to35 years, normal thyroid, liver and kidney, normal sperm count according to WHO criteria, taking no metformin in previous 8 weeks, normal hysterosalpingography Exclusion criteria: mullerian anomaly, abnormal sperm count, thyroid, liver or kidney dysfunction
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical pregnancy rate. Timepoint: three months and half after starting the treatment. Method of measurement: trans vaginal sonography.;Ovulation rate. Timepoint: two months and half after starting the treatment. Method of measurement: transvaginal sonography. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFatemeh Sarvi
Tehran University of Medical Science and Health Service, Shariati Hospital
Outcome results
None listed