pain reduction in dentistry

Comparative Study of Acetaminophen, Ibuprofen and Combination Effects for Pain Relief Following Tooth Extraction in Children under Local Anesthesia

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201103123109N2

Enrollment

105

Registered

2011-04-21

Start date

2008-08-22

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

teeth pain due to extraction. Analgesic,antipyretic and antiinflammatory drugs

Interventions

Intervention 1: group 1 received acetaminophen syrup 15mg/kg one hour before tooth extraction. Intervention 2: Group 2 received ibuprofen syrup 5mg/kg one hour before tooth extraction. Intervention 3

Treatment - Drugs

group 1 received acetaminophen syrup 15mg/kg one hour before tooth extraction

Group 2 received ibuprofen syrup 5mg/kg one hour before tooth extraction

Group 3 received acetaminophen 7.5 mg/kgand ibuprofen syrup 2.5mg/kg one hour before tooth extraction

Eligibility

Sex/Gender

All

Age

6 Years to 11 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: 6-11 years old, referred to dental clinic for first time, the mooler tooth must be extracted Exclusion criteria : any disease such as asthma, hypersensitivity or allergy to drugs

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: 0 and 15 min after tooth extraction. Method of measurement: Children’s Hospital of Eastern Ontario Pain Scale(CHEOPS).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Zeraati

Hamadan University of Medical Sciences

zeraati@umsha.ac.ir+98 81182762957 ext. 206

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026