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Evaluating the effects of rosemary capsule as adjunctive treatment in major depressive disorder

Evaluation of the effects of standardized hydroalcoholic extract of rosemary (Rosmarinus officinalis L.) capsule as adjunctive treatment in major depressive disorder

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110310006026N11
Enrollment
44
Registered
2019-11-07
Start date
2019-11-11
Completion date
Unknown
Last updated
2019-12-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

major depressive disorder. Mood disorder due to known physiological condition with major depressive-like episode

Interventions

Intervention 1: Intervention group: One capsule daily (each capsule containing about 500 mg of extract) for 8 weeks. Intervention 2: Control group:They receive one 500 mg capsules of placebo daily fo

Sponsors

Kerman University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 55 Years

Inclusion criteria

Inclusion criteria: Outpatient with Major Depression Based on DSM-5 Criterion, 18-55 years old, depressed patient who has never been on medication and is a candidate for SSRI treatment.

Exclusion criteria

Exclusion criteria: Pregnancy, lactation, having underlying medical or psychiatric illnesses, hypersensitivity reactions to rosemary, people at high risk of suicide, mental retardation - dependence on a variety of substances

Design outcomes

Primary

MeasureTime frame
Anxiety. Timepoint: At the beginning of the study and ,the fourth and eight weeks after the beginning of the study. Method of measurement: Hospital Anxiety Depression Scale (anxiety sub-scale).;Depression. Timepoint: At the beginning of the study and ,the fourth and eight weeks after the beginning of the study. Method of measurement: Beck Depression Inventory second edition.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactFatemeh Dabaghzadeh

Kerman University of Medical Sciences

fatemeh_dabaghzadeh@yahoo.com+98 34 1320 5034

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026