pain relief after CABG surgery. Acute pain
Conditions
Interventions
Intervention 1: Intervention group received 800 mg orally two hours before surgery and 400 mg two hours post extubation. Intervention 2: control group received placebo with same period.
Prevention
Placebo
Intervention group received 800 mg orally two hours before surgery and 400 mg two hours post extubation.
control group received placebo with same period.
Sponsors
Ahvaz Jundishapur University of Medical Sciences
Eligibility
Sex/Gender
Male
Age
20 Years to 70 Years
Inclusion criteria
Inclusion criteria: Inclusion criteria: men aged 20-70 years undergoing coronary artery bypass graft surgery. Exclusion criteria: history of chronic analgesic use (nonsteroidal anti-inflammatory drugs, opioids, or paracetamol); tranquilizer, anticonvulsant, or antidepressant use; alcohol dependence; malabsorption; hepatic and renal insufficiency; emergency surgery; previous cardiac surgery; left ventricular dysfunction (ejection fraction <40%); preoperative use of inotropic agents or intraaortic balloon pump; and allergy to the study drugs. Patients undergoing redo sternotomy were also excluded from the study.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Morphine consumpsion. Timepoint: 2, 6, 12, 24 hours post extubation. Method of measurement: medical records. | — |
Secondary
| Measure | Time frame |
|---|---|
| Pain. Timepoint: 2, 6, 12, 18 hours after extubation. Method of measurement: clinical evaluation (NRS). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Mehdi Dehghani Firouzabadi
Ahvaz Jundishapur University of Medical Sciences
Outcome results
None listed