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Comparison of two interventions on IVF outcome

Luteal phase estradiol versus luteal phase GnRH antagonist administration: their effects on antral follicular size coordination and basal hormonal levels

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201103052568N2
Enrollment
30
Registered
2011-05-03
Start date
2011-01-21
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

complications associated with artificial fertilization. Complication associated with artificial fertilization, unspecified

Interventions

Intervention 1: In intervention group one GNRH antagonist ampule is infused subcutaneusly on 25th of first cycle . Intervention 2: in control group 4 mg Estradiol tab daily administered from 20th day
Treatment - Drugs
In intervention group one GNRH antagonist ampule is infused subcutaneusly on 25th of first cycle .
in control group 4 mg Estradiol tab daily administered from 20th day of first cycle to 2nd day of second cycle.

Sponsors

Tehran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 35 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : 20-35 years old , male factor infertility , candidate for IVF , regular menstrual cycles , normal Body mass index (BMI) . Exclusion criteria :Those with history of hormone therapy for the past preceding 3 months , single ovary .

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Size of antral follicles. Timepoint: 20 days before intervention and 10 days after intervention. Method of measurement: transvaginal sonography.

Secondary

MeasureTime frame
Serum FSH. Timepoint: 20 days before intervention and 10 days after intervention. Method of measurement: blood sample.;Serum inhibin. Timepoint: 20 dayes before intervention and 10 dayes after intervention. Method of measurement: blood sample.;Serum Estradiol. Timepoint: 20 days before intervention and 10 days after intervention. Method of measurement: Blood sample.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHaleh Rahmanpour

Thran University of Medical Sciences

haleh509@gmail.com+98 66939320

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026