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Effect of dexamethasone on the goiterous size

Effect of intrathyroidal dexamethasone injection on the goiterous size, clinical and biochemical course of goiterous Hashimoto's thyroiditis with subclinical hypothyroidism

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT201103023565N3
Enrollment
40
Registered
2011-03-29
Start date
2010-11-05
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Goiterous Hashimoto's thyroiditis with subclinical Hyothyroidism.

Interventions

Intervention 1: Dexamethasone injection protocol within three months with needle No 25 (0/25 mm) under ultrasound guidance. Intervention 2: Patients in control group followed their routine life activ
Treatment - Drugs
Dexamethasone injection protocol within three months with needle No 25 (0/25 mm) under ultrasound guidance
Patients in control group followed their routine life activities without any therapeutic plan

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
15 Years to 70 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria: goiterous Hashimoto's thyroiditis with subclinical hypothyroidism, TSH = 10 mIU/L, AntiTPO + or AntiTG Exclusion criteria: Age between 15 and more than70, Use of corticosteroids therapy dose in the past six months for any reason, Use of antithyroid drugs at the baseline, Psychotic and psycho somatic diseases, Atrophic form of goiterous Hashimoto's thyroiditis, no consent to participate in the study

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
(TSH) Thyroid Stimulating Hormone. Timepoint: Baseline, the end of the third month and sixth month end. Method of measurement: Laboratory.

Secondary

MeasureTime frame
Antibody Against Thyroid Peroxidase (Anti TPO). Timepoint: Baseline, the end of the third month and sixth month end. Method of measurement: Laboratory.;Goiterous size. Timepoint: Baseline, the end of the third month and sixth month end. Method of measurement: Radiology.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr Akbar Aliasgharzadeha

Emam Reza hospital

asgharzadeha@gmail.com+98 914 402 4918

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026