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Efficacy of Gabapentin on flushing in menopausal women

Randomized placebo controlled clinical trial of the efficacy of Gabapentin on flushing in menopausal women

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT201103011107N4
Enrollment
60
Registered
2011-05-05
Start date
2010-06-22
Completion date
Unknown
Last updated
2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Flushing. Menopausal and female climacteric states

Interventions

Intervention 1: Intervention group: Gabapentin Capsule 300 mg- TDS-during 3 months. Intervention 2: Control group: Placebo as capsules, three times a day for 3 months.
Treatment - Drugs
Placebo
Intervention group: Gabapentin Capsule 300 mg- TDS-during 3 months
Control group: Placebo as capsules, three times a day for 3 months

Sponsors

Jundishapour Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
40 Years to 55 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria : Elapsing one year of last menstrual phase(LMP), Follicle-stimulating hormone (FSH) more than 40IU/L and not using any drugs that affect on hot flush symptoms. Exclusion criteria : happening Gabapentin side effects, noncompliance and coexistence of systemic disease

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Flushing severity. Timepoint: Before intervention, 1 month after intervention, 2months later and 3 months later after intervention. Method of measurement: Visual Analoge Scale.

Secondary

MeasureTime frame
Flushing duration. Timepoint: Before intervention, 1 month after intervention, 2months later and 3 months later after intervention. Method of measurement: Patients notation.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Solmaz Natanj

Ahvaz Jundishapour Medical University

Solmaznatanj@Yahoo.com+98 61 1222 2922

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026