Infertility. Female infertility
Conditions
Interventions
Intervention 1: Intervention group: In this group, 3 milligrams of oral melatonin (Razak Pharmaceutical Company) will be prescribed every night from the second day of the cycle until the egg retrieval
Sponsors
Vice chancellor for Research, Tabriz University Of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 42 Years
Inclusion criteria
Inclusion criteria: Using assisted reproductive methods for the first time Presence of sperm in husband's semen Number of antral follicles, less than or equal to 6 Anti-Mullerin hormone less equal to one Follicle stimulating hormone FSH on the 3rd day of menstruation is more equal to 10 consent to participate in the study Age 18 to 42 years BMI between 19 and 29
Exclusion criteria
Exclusion criteria: People with Müllerian anomalies and other structural causes of infertility People who use anticoagulants such as warfarin
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of resulted oocytes. Timepoint: The day of oocytes pick up. Method of measurement: Microscopic evaluation.;Quality of resulted oocytes. Timepoint: The day of oocytes pick up. Method of measurement: Microscopic evaluation.;Fertilization rate. Timepoint: Fertilization evaluation will be done between 16 and 20 hours after IVF-ICSI. Method of measurement: Microscopic evaluation. | — |
Secondary
| Measure | Time frame |
|---|---|
| Implantation rate. Timepoint: 4-6 weeks after embryos transfer. Method of measurement: Transvaginal ultrasound.;Chemical pregnancy. Timepoint: Two weeks after pregnancy. Method of measurement: Serum BHCG.;Clinical pregnancy. Timepoint: Two weeks after pregnancy. Method of measurement: Visualization of a pregnancy sac containing a heartbeat on ultrasound. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr.Aliye Ghasemzadeh
Tabriz University of Medical Sciences
Outcome results
None listed