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Comparison of sildenafil and isorbid effects on embery transfer outcome in patients with recurrent implantation failure

Comparison of sildenafil and isorbid effects on embery transfer outcome in patients with recurrent implantation failure

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20110301005942N8
Enrollment
90
Registered
2021-11-15
Start date
2021-08-29
Completion date
Unknown
Last updated
2021-11-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility. Female infertility of tubal origin

Interventions

Intervention 1: Intervention group 1: Intervention group 1. For patients on day 1-3 of the menstrual cycle, vaginal ultrasound is performed and in the absence of ovarian cysts and space-occupying lesi

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
15 Years to 40 Years

Inclusion criteria

Inclusion criteria: 15 to 40 years Patients with a history of double implantation failure who have at least 2 frozen embryos for transfer will be included in the study with consent.

Exclusion criteria

Exclusion criteria: 1.Treatment with hypertension drugs 2.Myoma, adenomyosis, congenital malformations of the uterus, endometriosis 3.History of cardiovascular or renal or liver disease or use of nonsteroidal anti-inflammatory drugs and any chronic disease Reluctance to participate in the study

Design outcomes

Primary

MeasureTime frame
Evaluation of endometrial thickness. Timepoint: The initial evaluation of endometrial thickness is performed on day 1 to 3 and then 10 days later. Method of measurement: Trans vaginal sonograghy.;BHCG titer examination. Timepoint: Chemical pregnancy 2 weeks after embryo transfer. Method of measurement: Chemical pregnancy with BHCG.

Secondary

MeasureTime frame
Clinical pregnancy. Timepoint: 4 weeks after embryo transfer. Method of measurement: Trans vaginal sonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Aliye Ghasemzadeh

Tabriz University of Medical Sciences

alghasemzadeh@yahoo.co.uk+98 41 3557 1113

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026