Evaluation of L-carnitine effect on prevention of chemotherapy-induced oral mucositis , A prospective, randomized, double-blind, controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT201102265914N1

Enrollment

Registered

2017-10-02

Start date

2016-03-19

Completion date

Unknown

Last updated

2018-02-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

mucositis. Oral mucositis (ulcerative)

Interventions

Intervention 1: l-carnitine 1gr tablets 3 times a day for 3 weeks. Intervention 2: placebo 1gr tablets 3 times a day for 3 weeks.

Treatment - Drugs

Placebo

l-carnitine 1gr tablets 3 times a day for 3 weeks

placebo 1gr tablets 3 times a day for 3 weeks

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Exclusion criteria: the risk of side effects such as nausea or whenever the patient refuse to participate in the study Inclusion criteria of the study: bedridden in Oncology unit, consent to participate in the study, without using drugs or any vitamin and mineral carnitine in the past 8 weeks, aged over 18 years

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Oral mucositis. Timepoint: weekly. Method of measurement: observation.;CBC. Timepoint: weekly. Method of measurement: blood sample.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactShima Hatamkhani

Faculty of Pharmacy of Urmia

hatamkhani@razi.tums.ac.ir+98 44 3275 4990

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026