Glaucoma. Ocular Hypertension,primary open angle glaucoma
Conditions
Interventions
Intervention 1: Eyedrop latanoprost 0.005% once daily at 9 PM in one eye (group 1) and every other day dose in the other eye (group 2) at month1. Intervention 2: Eyedrop latanoprost 0.005% once daily
Treatment - Drugs
Eyedrop latanoprost 0.005% once daily at 9 PM in one eye (group 1) and every other day dose in the other eye (group 2) at month1.
Eyedrop latanoprost 0.005% once daily at 9 PM in one eye (group 2) and every other day dose in the other eye (group 1) at month 2.
Sponsors
Eye research center,Rassoul Akram Hospital, Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
30 Years to No maximum
Inclusion criteria
Inclusion criteria: The inclusion criteria are: Age =30 years, IOP =22 and =32 mmHg without any IOP lowering medication, cup to disc ratio =0.6, mean deviation of = -6 decibel in perimetry and open angles on gonioscopy. Patients with a history of prior ocular surgery, uveitis, herpetic keratitis, and allergy to latanoprost are excluded
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraocular pressure (IOP). Timepoint: 24 hours before instillation of latanoprost, baseline IOP was measured 3 times ,at 9AM,4PM,and 9PM and again after one and two months of drug usage,based on assigned protocol of drug instillation,were measured at the same time points. Method of measurement: Calibrated Goldmann applanation tonometer. | — |
Secondary
| Measure | Time frame |
|---|---|
| Side effects related to drug. Timepoint: At each time visit after instillation of drug ,during 2-month period of study. Method of measurement: Anterior segment exam by slit lamp biomicroscopy,posterior segment exam by funduscopy lenses, visual acuity test by Snellen chart and patients own description of side effects like significant Itching,redness and burning sensation. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactnaveed Nilforushan
Eye research center,Rassoul akram Hospital Tehran University of Medical Sciences
Outcome results
None listed